Health Discovery: Selenium, Vitamin E Don't Help After All

Do vitamin E and selenium help prevent prostate cancer? The answer is no, according to findings from a major trial with 35,000 men. The SELECT study, sponsored by the National Cancer Institute and begun in 2001, was stopped early, in September, after finding no evidence of any benefit from either supplement.

The news disappointed many cancer experts, says Elise Cook, M.D., a study researcher and a cancer prevention specialist at M.D. Anderson Cancer Center in Houston. But it provides important information about what doesn’t work. Cook says many men had been reluctant to join the study because they were already taking vitamin E for heart as well as prostate health. “Since then, other studies have shown that it really didn’t help their hearts, either,” she says.